Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562983 | 0.82 | PIN1 (0.48) | POLBSMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL8598588 | 0.81 | POLB (0.40) | POLBSMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL8627624 | 0.79 | MAPT (0.39) | POLBSMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL8599584 | 0.79 | MEN1 (0.39) | POLBSMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL8596309 | 0.79 | MEN1 (0.38) | POLBSMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL8624593 | 0.77 | MAPT (0.35) | POLBSMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL8925738 | 0.77 | GSK3A (0.39) | POLBSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8628924 | 0.76 | PIM1 (0.37) | POLBSMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL8560319 | 0.75 | POLB (0.46) | POLBSMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL8562402 | 0.75 | POLB (0.46) | POLBSMN1; SMN2ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |