Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3255349 | 0.94 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTNPC1RAB9ANFKB1 | |
| SCHEMBL3849724 | 0.84 | PDE4A (0.42) | SMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL2364705 | 0.83 | KAT8 (0.52) | SMN1; SMN2MAPTPPARAPPARGRARB | |
| SCHEMBL31271554 | 0.79 | CYP4F2 (0.45) | SMN1; SMN2MAPTKDM4EHSD17B10 | |
| SCHEMBL3252310 | 0.79 | NFKB1 (0.53) | SMN1; SMN2MAPTPPARAPPARGRARB | |
| SCHEMBL345197 | 0.76 | PARP1 (0.55) | SMN1; SMN2MAPTPPARAPPARGRARB | |
| SCHEMBL20476379 | 0.75 | PPARA (0.57) | SMN1; SMN2MAPTPPARAPPARGRARB | |
| SCHEMBL1329013 | 0.74 | MAPT (0.43) | SMN1; SMN2MAPTKDM4EGALK1 | |
| SCHEMBL28773091 | 0.74 | PPARA (0.58) | MAPTPPARAPPARGRARBKAT8 | |
| SCHEMBL20178627 | 0.73 | MAPT (0.61) | SMN1; SMN2MAPTPPARAPPARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846684-A2 | Process for producing 2-halo-nicotinic acid derivatives and precursors thereto | REILLY INDUSTRIES, INC. (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5493028-A | Processes for producing 2-Halo-nicotinic acid derivatives and precursors thereto | REILLY INDUSTRIES, INC. (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0633880-A1 | PROCESSES FOR PRODUCING 2-HALO-NICOTINIC ACID DERIVATIVES AND PRECURSORS THERETO | REILLY INDUSTRIES, INC. (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993018005-A2 | PROCESSES FOR PRODUCING 2-HALO-NICOTINIC ACID DERIVATIVES AND PRECURSORS THERETO | REILLY INDUSTRIES, INC. (US) | 1993-09-16 | — | — | WO | disclosed |