SCHEMBL8628651

SCHEMBL8628651

Nc1cc(N)cc(C(=O)Oc2ccc(O)cc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
THRB P10828 1/20 0.47
BLM P54132 1/20 0.47
CASP6 P55212 1/20 0.47
GFER P55789 1/20 0.47
NSD2 O96028 1/20 0.47
KMT2A Q03164 5/20 0.45
F2 P00734 3/20 0.45
PRSS1 P07477 3/20 0.45
PRSS2 P07478 3/20 0.45
PRSS3 P35030 3/20 0.45
PKM P14618 1/20 0.45
NR1H4 Q96RI1 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PARP10 Q53GL7 2/20 0.43
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13834260 0.95 MAPT (0.44) MAPTTDP1KDM4EGLAGAA
SCHEMBL20348502 0.92 PRSS1 (0.50) MAPTTDP1NSD2KMT2AF2
SCHEMBL13292728 0.89 F2 (0.56) MAPTTDP1KDM4EGLAGAA
SCHEMBL13292750 0.87 MAPT (0.46) MAPTTDP1GAANSD2KMT2A
SCHEMBL24586934 0.84 PARP10 (0.64) KMT2AF2PRSS1PRSS2PRSS3
SCHEMBL2633411 0.83 NSD2 (0.62) MAPTTDP1KDM4ENSD2KMT2A
SCHEMBL9003865 0.83 F2 (0.63) MAPTTDP1KDM4EGLAGAA
SCHEMBL10785180 0.82 CA12 (0.52) MAPTTDP1NSD2KMT2AF2
SCHEMBL11191457 0.82 NSD2 (0.52) MAPTTDP1NSD2KMT2AF2
SCHEMBL13292767 0.82 KMT2A (0.43) MAPTTDP1NSD2KMT2AF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130237040-A1 RESIN COMPOSITION, LAMINATE AND PROCESS FOR PRODUCTION THEREOF, STRUCTURE AND PROCESS FOR PRODUCTION THEREOF, AND PROCESS FOR PRODUCTION OF ELECTRONIC DEVICE ASAHI GLASS COMPANY, LIMITED (JP) 2013-09-12 US disclosed
US-5747625-A Silicate group-containing polyimide NIPPON STEEL CHEMICAL CO., LTD. (JP) 1998-05-05 US disclosed