Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.63 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.63 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128037 | 0.95 | F2 (0.58) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL346698 | 0.92 | PRSS1 (0.71) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL107649 | 0.92 | PRSS1 (0.71) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL347429 | 0.92 | PRSS1 (0.71) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL688276 | 0.90 | HSD17B10 (0.59) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL16493489 | 0.90 | HSD17B10 (0.59) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL9696072 | 0.90 | HSD17B10 (0.59) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL740606 | 0.90 | HSD17B10 (0.59) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL777813 | 0.90 | HSD17B10 (0.59) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL22310501 | 0.86 | PRSS1 (0.65) | F2PRSS1PRSS2PRSS3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491201-A | HEAT/CHEMICAL RESISTANCE; HIGH MECHANICAL STRENGTH | THE DOW CHEMICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| EP-0524419-B1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5391806-A | A storage stable chromogens as color-developing agent or stabilizers | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5338828-A | Mesogenic cyclic imino ether-containing compositions and polymerization products thereof | THE DOW CHEMICAL COMPANY (US) | 1994-08-16 | — | — | US | disclosed |
| US-5281675-A | Liquid crystal polymers | THE DOW CHEMICAL COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5270281-A | Chromogenic compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0524419-A1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |