Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963648 | 0.76 | TP53 (0.44) | TSHRNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL2733147 | 0.75 | TSHR (0.65) | TSHRMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL2733150 | 0.75 | TSHR (0.65) | TSHRMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL8821125 | 0.75 | KMT2A (0.47) | TSHRMEN1KMT2ANPC1TP53 | |
| SCHEMBL8854135 | 0.72 | POLB (0.48) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8854131 | 0.72 | POLB (0.48) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL13302556 | 0.69 | NAPRT (0.44) | TSHRNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL463912 | 0.68 | TSHR (0.56) | TSHRMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL6495106 | 0.67 | TSHR (0.45) | TSHRMEN1KMT2ANPC1RAB9A | |
| Dimethylamine SCHEMBL8847032 | 0.67 | TDP1 (0.77) | TSHRNPC1TP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10291980-A | — | — | None | — | — | JP | disclosed |
| JP-H10291980-A | OPTICALLY ACTIVE 4,5-DIPHENYL-2-IMIDAZOLIDINONE DERIVATIVE AND PRODUCTION OF OPTICALLY ACTIVE ALPHA-AMINOPHOSPHORIC ACID WITH THE SAME | SHIRATORI SEIYAKU KK | 1998-11-04 | — | — | JP | disclosed |