Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733147 | 1.00 | TSHR (0.65) | TSHRKMT2AMEN1ATMALDH1A1 | |
| SCHEMBL14569802 | 0.87 | KMT2A (0.72) | TSHRKMT2AMEN1ATMALDH1A1 | |
| SCHEMBL2731404 | 0.76 | TSHR (0.42) | TSHRKMT2AMEN1ATMALDH1A1 | |
| SCHEMBL24052064 | 0.76 | TSHR (0.42) | TSHRKMT2AMEN1ATMALDH1A1 | |
| SCHEMBL8821125 | 0.76 | KMT2A (0.47) | TSHRKMT2AMEN1ATMALDH1A1 | |
| SCHEMBL13557184 | 0.76 | KMT2A (0.50) | TSHRKMT2AMEN1ATMALDH1A1 | |
| SCHEMBL8628659 | 0.75 | TSHR (0.49) | TSHRKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9508090 | 0.74 | KMT2A (0.45) | TSHRKMT2AMEN1ATMALDH1A1 | |
| SCHEMBL9511305 | 0.74 | KMT2A (0.45) | TSHRKMT2AMEN1ATMALDH1A1 | |
| SCHEMBL9511293 | 0.74 | KMT2A (0.45) | TSHRKMT2AMEN1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632917-B1 | NOVEL PHASE TRANSFER CATALYSTS | UNIV SINGAPORE (SG) | 2016-04-20 | — | — | EP | disclosed |
| EP-2632917-A1 | NOVEL PHASE TRANSFER CATALYSTS | National University of Singapore (SG) | 2013-09-04 | — | — | EP | disclosed |
| US-20130217889-A1 | NOVEL PHASE TRANSFER CATALYSTS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2013-08-22 | — | — | US | disclosed |
| WO-2012057709-A1 | NOVEL PHASE TRANSFER CATALYSTS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217889-A1 | NOVEL PHASE TRANSFER CATALYSTS | POLR2B, POLR1A, POLR2A | TSHR 1696/4885KMT2A 1808/4885MEN1 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.