Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490504 | 0.87 | CYP1A2 (0.55) | ATMSMN1; SMN2CYP1A2MAPK1L3MBTL1 | |
| SCHEMBL949323 | 0.87 | ALDH1A1 (0.61) | ATMSMN1; SMN2CYP1A2MAPK1L3MBTL1 | |
| SCHEMBL3439885 | 0.85 | ATM (0.62) | ATMSMN1; SMN2CYP1A2MAPK1L3MBTL1 | |
| SCHEMBL22878227 | 0.84 | ATM (0.53) | ATMSMN1; SMN2CYP1A2MAPK1L3MBTL1 | |
| SCHEMBL17285866 | 0.84 | NPC1 (0.64) | ATMSMN1; SMN2CYP1A2MAPK1L3MBTL1 | |
| SCHEMBL17284619 | 0.84 | ATM (0.53) | ATMSMN1; SMN2CYP1A2MAPK1L3MBTL1 | |
| SCHEMBL2606057 | 0.84 | NPC1 (0.69) | ATMSMN1; SMN2CYP1A2MAPK1L3MBTL1 | |
| SCHEMBL10722542 | 0.84 | ATM (0.85) | ATMSMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL19574089 | 0.84 | ATM (0.95) | ATMSMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL28366947 | 0.84 | ATM (0.85) | ATMSMN1; SMN2L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |