Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 6/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631538 | 0.93 | PTGS2 (0.37) | PTGS2PTGS1TRPV1F10 | |
| SCHEMBL8630982 | 0.92 | PTGS2 (0.37) | PTGS2PTGS1TRPV1F10MAPK14 | |
| SCHEMBL8630570 | 0.91 | F10 (0.37) | PTGS2PTGS1F10ENPP3 | |
| SCHEMBL8629119 | 0.89 | PTGS2 (0.38) | PTGS2PTGS1TRPV1F10 | |
| SCHEMBL8631947 | 0.89 | F10 (0.46) | PTGS2PTGS1F10 | |
| SCHEMBL8632159 | 0.88 | F10 (0.38) | PTGS2PTGS1F10ALOX5APFEN1 | |
| SCHEMBL8633155 | 0.85 | PTGS2 (0.39) | PTGS2PTGS1TRPV1F10 | |
| SCHEMBL8629017 | 0.85 | PTGS2 (0.45) | PTGS2PTGS1F10 | |
| SCHEMBL8631518 | 0.84 | PTGS2 (0.50) | PTGS2PTGS1TRPV1F10ALOX5AP | |
| SCHEMBL8627953 | 0.83 | PTGS2 (0.42) | PTGS2PTGS1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |