Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629851 | 0.90 | KMT2A (0.60) | RAB9AMAPTKMT2AMEN1HTT | |
| SCHEMBL8630926 | 0.88 | MAPT (0.40) | RAB9AMAPTKMT2AMEN1HTT | |
| SCHEMBL8627539 | 0.87 | SLC2A1 (0.49) | RAB9AMAPTKMT2AMEN1HTT | |
| SCHEMBL8540029 | 0.87 | MAPT (0.48) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL8630090 | 0.85 | NTRK1 (0.46) | MAPTKMT2AMEN1HTTHSD17B10 | |
| SCHEMBL8626823 | 0.84 | MAPT (0.64) | RAB9AMAPTKMT2AMEN1HTT | |
| SCHEMBL8629943 | 0.83 | MAPT (0.50) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL8795214 | 0.83 | MAPT (0.41) | MAPTKMT2AMEN1HTTHSD17B10 | |
| SCHEMBL8630938 | 0.81 | S1PR1 (0.45) | MAPTKMT2AMEN1HTTHSD17B10 | |
| SCHEMBL5193130 | 0.81 | MAPT (0.48) | MAPTKMT2AMEN1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847126-A | N-azinyl-N'-(het) arylsulphonyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0645386-B1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| US-5696257-A | INTERMEDIATES FOR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| US-5580842-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| US-5476936-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-19 | — | — | US | disclosed |
| EP-0645386-A1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1995-03-29 | — | — | EP | disclosed |
| EP-0178101-B1 | HERBICIDAL ORTHO-HETEROCYCLIC SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-16 | — | — | EP | disclosed |
| US-4756742-A | Herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-07-12 | — | — | US | disclosed |
| US-4755211-A | Herbicial ortho-heterocycllic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4707178-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-17 | — | — | US | disclosed |
| US-4707179-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-17 | — | — | US | disclosed |
| US-4662931-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| US-4657578-A | Herbicidal ortho-heterocyclic sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-14 | — | — | US | disclosed |
| US-4655817-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-07 | — | — | US | disclosed |
| US-4634465-A | PRE- AND POSTEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1987-01-06 | — | — | US | disclosed |
| EP-0178101-A1 | Herbicidal ortho-heterocyclic sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-16 | — | — | EP | disclosed |
| EP-0099339-A2 | Condensed N-phenylsulfonyl-N'-pyrimidinyl and triazinyl urea | CIBA-GEIGY AG (CH) | 1984-01-25 | — | — | EP | disclosed |