Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629039 | 0.92 | HTT (0.40) | MAPTTSHRNPSR1HTTALDH1A1 | |
| SCHEMBL8626823 | 0.89 | MAPT (0.64) | MAPTTSHRNPSR1MAPK1L3MBTL1 | |
| SCHEMBL8540029 | 0.85 | MAPT (0.48) | MAPTTSHRNPSR1MAPK1L3MBTL1 | |
| SCHEMBL8628783 | 0.83 | RAB9A (0.49) | MAPTTSHRNPSR1MAPK1L3MBTL1 | |
| SCHEMBL8629522 | 0.80 | MAPT (0.46) | MAPTTSHRNPSR1MAPK1L3MBTL1 | |
| SCHEMBL5193130 | 0.78 | MAPT (0.48) | MAPTL3MBTL1LMNAHTTALDH1A1 | |
| SCHEMBL8629851 | 0.77 | KMT2A (0.60) | MAPTTSHRNPSR1MAPK1L3MBTL1 | |
| SCHEMBL8630926 | 0.76 | MAPT (0.40) | MAPTTSHRNPSR1MAPK1L3MBTL1 | |
| SCHEMBL8627539 | 0.74 | SLC2A1 (0.49) | MAPTTSHRNPSR1MAPK1LMNA | |
| SCHEMBL8628976 | 0.74 | ALDH1A1 (0.47) | MAPTTSHRNPSR1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847126-A | N-azinyl-N'-(het) arylsulphonyl-ureas | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0645386-B1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| US-5696257-A | INTERMEDIATES FOR HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| US-5580842-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| US-5476936-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-19 | — | — | US | disclosed |
| EP-0645386-A1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1995-03-29 | — | — | EP | disclosed |
| EP-0097122-B1 | N-HETEROCYCLOSULFONYL-N'-PYRIMIDINYL AND TRIAZINYL UREAS | CIBA-GEIGY AG (CH) | 1989-05-31 | — | — | EP | disclosed |
| US-4549898-A | PREEMERGENT AND POSTEMERGENT HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1985-10-29 | — | — | US | disclosed |
| EP-0097122-A2 | N-heterocyclosulfonyl-N'-pyrimidinyl and triazinyl ureas | CIBA-GEIGY AG (CH) | 1983-12-28 | — | — | EP | disclosed |