Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993655 | 0.90 | CHRNA7 (0.47) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9070398 | 0.90 | CHRNA7 (0.47) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL7995742 | 0.82 | SMN1; SMN2 (0.46) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9070091 | 0.82 | SMN1; SMN2 (0.46) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL7993705 | 0.76 | CHRNA7 (0.47) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL7996219 | 0.76 | CHRNA1 (0.47) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL1019610 | 0.76 | CHRNA7 (0.64) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9070394 | 0.76 | CHRNA1 (0.47) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9070391 | 0.76 | CHRNA7 (0.47) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL1019609 | 0.76 | CHRNA7 (0.64) | CHRNA1CHRNA3CHRNA7SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750704-A | INSECTICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5428032-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1995-06-27 | — | — | US | disclosed |
| US-5001138-A | Insecticides | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | disclosed |