Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777498 | 0.93 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL7779573 | 0.89 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7780074 | 0.89 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL216154 | 0.89 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7777584 | 0.88 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL7773183 | 0.86 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL7779266 | 0.86 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL7779916 | 0.84 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL7779420 | 0.83 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL7773169 | 0.82 | PTGS2 (0.67) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |
| US-5580985-A | ANTIARTHRITIC AGENT; SIDE EFFECT REDUCTION | G. D. SEARLE & CO. (US) | 1996-12-03 | — | — | US | disclosed |
| US-5486534-A | 3,4-substituted pyrazoles for the treatment of inflammation | G. D. SEARLE & CO. (US) | 1996-01-23 | — | — | US | disclosed |