Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627529 | 0.94 | MAPT (0.53) | MAPTL3MBTL1ALDH1A1POLBMRGPRX4 | |
| SCHEMBL8627523 | 0.84 | MAPT (0.45) | MAPTL3MBTL1ALDH1A1POLBMRGPRX4 | |
| SCHEMBL8629313 | 0.84 | MAPT (0.45) | MAPTL3MBTL1ALDH1A1POLBMRGPRX4 | |
| SCHEMBL8631524 | 0.82 | MAPT (0.47) | MAPTL3MBTL1ALDH1A1POLBMRGPRX4 | |
| SCHEMBL6613426 | 0.79 | MAPT (0.54) | MAPTL3MBTL1ALDH1A1POLBLMNA | |
| SCHEMBL8698390 | 0.79 | MAPT (0.45) | MAPTL3MBTL1ALDH1A1POLBLMNA | |
| SCHEMBL8693809 | 0.79 | KMT2A (0.43) | MAPTL3MBTL1ALDH1A1POLBMRGPRX4 | |
| SCHEMBL8773158 | 0.78 | MAPT (0.65) | MAPTL3MBTL1ALDH1A1POLBLMNA | |
| SCHEMBL29607042 | 0.78 | MAPT (0.65) | MAPTL3MBTL1ALDH1A1POLBLMNA | |
| SCHEMBL8696729 | 0.78 | GRM5 (0.41) | ALDH1A1GRM5PPARGFFAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792872-A2 | 2,6-substituted pyridine derivatives, their preparation and their use as herbicidal agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | claimed |
| US-5807804-A | CONTROLLING WEEDS | AMERICAN CYANAMID COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| US-5710106-A | Substituted pyridine herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| EP-0792872-A2 | 2,6-substituted pyridine derivatives, their preparation and their use as herbicidal agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |