Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627523 | 1.00 | MAPT (0.45) | MAPTL3MBTL1POLBALDH1A1MRGPRX4 | |
| SCHEMBL8627529 | 0.89 | MAPT (0.53) | MAPTL3MBTL1POLBALDH1A1MRGPRX4 | |
| SCHEMBL8633367 | 0.88 | PPARG (0.43) | L3MBTL1MRGPRX4LMNAPPARGGRM5 | |
| SCHEMBL8631524 | 0.85 | MAPT (0.47) | MAPTL3MBTL1POLBALDH1A1MRGPRX4 | |
| SCHEMBL8628947 | 0.84 | MAPT (0.48) | MAPTL3MBTL1POLBALDH1A1MRGPRX4 | |
| SCHEMBL8628556 | 0.81 | GRM5 (0.47) | MRGPRX4LMNAPPARGGRM5KCNH2 | |
| SCHEMBL8694570 | 0.81 | GRM5 (0.43) | L3MBTL1MRGPRX4PPARGGRM5KCNH2 | |
| SCHEMBL8692569 | 0.79 | PPARG (0.42) | MAPTL3MBTL1ALDH1A1MRGPRX4LMNA | |
| SCHEMBL15769129 | 0.78 | MAOB (0.47) | MRGPRX4PPARGGRM5MAOBKCNH2 | |
| SCHEMBL7009339 | 0.78 | KMO (0.47) | MAPTL3MBTL1POLBALDH1A1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792872-A2 | 2,6-substituted pyridine derivatives, their preparation and their use as herbicidal agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | claimed |
| US-5807804-A | CONTROLLING WEEDS | AMERICAN CYANAMID COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| US-5710106-A | Substituted pyridine herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| EP-0792872-A2 | 2,6-substituted pyridine derivatives, their preparation and their use as herbicidal agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |