Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.72 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10954211 | 0.98 | PARP1 (0.74) | PARP1VCAM1MAPK1LMNAMAPT | |
| SCHEMBL6561918 | 0.93 | VCAM1 (0.68) | PARP1VCAM1MAPK1LMNAMAPT | |
| SCHEMBL8625237 | 0.93 | PARP1 (0.64) | PARP1VCAM1MAPK1LMNAMAPT | |
| SCHEMBL8623024 | 0.91 | PARP1 (0.66) | PARP1VCAM1MAPK1LMNAMAPT | |
| SCHEMBL10955605 | 0.89 | VCAM1 (0.81) | PARP1VCAM1MAPK1LMNAMAPT | |
| SCHEMBL8622632 | 0.86 | PARP1 (0.59) | PARP1VCAM1MAPK1ALDH1A1TDP1 | |
| SCHEMBL30995722 | 0.85 | PARP1 (0.72) | PARP1LMNACASP6TSHR | |
| SCHEMBL1766442 | 0.85 | PARP1 (0.72) | PARP1LMNACASP6TSHR | |
| Iniparib SCHEMBL29354973 | 0.84 | PARP1 (1.00) | PARP1LMNAMAPTALDH1A1CASP6 | |
| SCHEMBL3181806 | 0.84 | PARP1 (0.70) | PARP1VCAM1MAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710334-A | PENDANT ETHER GROUPS, POLYIMIDES WITH IMPROVED SOLUBILITY, MELT FLOW STABILITY, PROCESSABILITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0572196-B1 | Polyimide, and preparation process of same | MITSUI TOATSU CHEMICALS (JP) | 1997-08-06 | — | — | EP | disclosed |
| US-5480965-A | BASED ON A NOVEL DIAMINO COMPOUND DERIVED FROM BENZOPHENONE STRUCTURE; FIBER REINFORCEMENT | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0572196-A1 | Polyimide, and preparation process of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-12-01 | — | — | EP | disclosed |