Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629981 | 0.89 | POLB (0.42) | F10PTGS2F2PTGS1 | |
| SCHEMBL8628007 | 0.88 | PTGS2 (0.40) | F10PTGS2F2PTGS1 | |
| SCHEMBL8631518 | 0.88 | PTGS2 (0.50) | F10PTGS2PTGS1 | |
| SCHEMBL8632452 | 0.87 | PTGS2 (0.40) | F10PTGS2F2PTGS1 | |
| SCHEMBL8634613 | 0.87 | PTGS2 (0.55) | F10PTGS2F2PTGS1 | |
| SCHEMBL8632198 | 0.85 | PTGS2 (0.41) | F10PTGS2F2PTGS1 | |
| SCHEMBL8634387 | 0.85 | PTGS2 (0.46) | F10PTGS2PTGS1 | |
| SCHEMBL8629546 | 0.85 | PTGS2 (0.49) | F10PTGS2F2PTGS1 | |
| SCHEMBL8635118 | 0.85 | F10 (0.46) | F10PTGS2F2PTGS1 | |
| SCHEMBL8631947 | 0.85 | F10 (0.46) | F10PTGS2F2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |