Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | STAMBP | O95630 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566297 | 0.91 | KMT2A (0.43) | KMT2AMEN1L3MBTL1MRGPRX4MAPT | |
| SCHEMBL8630305 | 0.84 | MRGPRX4 (0.44) | MRGPRX4 | |
| SCHEMBL8629531 | 0.84 | MRGPRX4 (0.44) | MRGPRX4ALDH1A1 | |
| SCHEMBL8632231 | 0.81 | KMT2A (0.56) | KMT2AMEN1L3MBTL1MAPTGAA | |
| SCHEMBL6565235 | 0.79 | EGLN1 (0.43) | — | |
| SCHEMBL8631264 | 0.78 | KMT2A (0.44) | KMT2AMEN1L3MBTL1MAPTGAA | |
| SCHEMBL8630494 | 0.77 | SMN1; SMN2 (0.51) | KMT2AMEN1L3MBTL1MAPTGAA | |
| SCHEMBL8630092 | 0.77 | MAPK14 (0.45) | KMT2AMEN1L3MBTL1MRGPRX4 | |
| SCHEMBL6567174 | 0.77 | GAA (0.45) | KMT2AMEN1L3MBTL1MAPTGAA | |
| SCHEMBL6567478 | 0.77 | KMT2A (0.48) | KMT2AMEN1L3MBTL1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726305-A | Substituted quinoline-2-carboxamides, their preparation and their use as pharmaceuticals, and intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-10 | — | — | US | disclosed |
| US-5719164-A | Substituted quinoline-2-carboxamides, their preparation and their use as pharmaceuticals, and intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |