Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434541 | 0.88 | GAA (0.62) | GAAL3MBTL1MAPTTP53TDP1 | |
| SCHEMBL1273114 | 0.87 | GAA (0.54) | GAAL3MBTL1MAPTTP53TDP1 | |
| SCHEMBL1273113 | 0.85 | GAA (0.53) | GAAL3MBTL1MAPTTP53TDP1 | |
| SCHEMBL13644031 | 0.81 | GAA (0.56) | GAAL3MBTL1TP53TDP1THRB | |
| SCHEMBL7655298 | 0.81 | GPR119 (0.51) | SMN1; SMN2 | |
| SCHEMBL1267275 | 0.79 | GAA (0.61) | GAAL3MBTL1MAPTTP53TDP1 | |
| SCHEMBL29251163 | 0.79 | CNR2 (0.41) | TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3319018 | 0.77 | GAA (0.59) | GAAL3MBTL1MAPTTP53TDP1 | |
| SCHEMBL10576741 | 0.77 | GAA (0.64) | GAAL3MBTL1MAPTTP53TDP1 | |
| SCHEMBL8426303 | 0.77 | GAA (0.54) | GAAL3MBTL1MAPTTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801173-A | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-09-01 | — | — | US | disclosed |