Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.57 |
| ▸ | CASP2 | P42575 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | F13A1 | P00488 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | THPO | P40225 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11875717 | 1.00 | PAOX (0.57) | PAOXCASP2CA12F13A1CA2 | |
| Acetic Acid SCHEMBL10585174 | 0.91 | CA12 (0.48) | PAOXCASP2CA12F13A1CA2 | |
| Acetic Acid SCHEMBL20388 | 0.91 | CA12 (0.48) | PAOXCASP2CA12F13A1CA2 | |
| Acetic Acid SCHEMBL3149055 | 0.91 | CA12 (0.48) | PAOXCASP2CA12F13A1CA2 | |
| Acetic Acid SCHEMBL2167992 | 0.91 | CA12 (0.48) | PAOXCASP2CA12F13A1CA2 | |
| Acetic Acid SCHEMBL9238796 | 0.91 | CA12 (0.48) | PAOXCASP2CA12F13A1CA2 | |
| Acetic Acid SCHEMBL2873750 | 0.89 | CA12 (0.46) | PAOXCASP2CA12F13A1CA2 | |
| Acetic Acid SCHEMBL2402864 | 0.89 | CA12 (0.46) | PAOXCASP2CA12F13A1CA2 | |
| Acetic Acid SCHEMBL2873747 | 0.89 | CA12 (0.46) | PAOXCASP2CA12F13A1CA2 | |
| Acetic Acid SCHEMBL9759748 | 0.89 | CA12 (0.46) | PAOXCASP2CA12F13A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540990-B1 | Tablet-shaped processing agent and method for processing silver halide photographic light sensitive materials | KONISHIROKU PHOTO IND (JP) | 1998-07-15 | — | — | EP | disclosed |
| US-5366853-A | Bleaches for photographic films | KONICA CORPORATION (JP) | 1994-11-22 | — | — | US | disclosed |
| US-5362610-A | Photographic processing agent | KONICA CORPORATION (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0540990-A1 | Tablet-shaped processing agent and method for processing silver halide photographic light sensitive materials | KONICA CORPORATION (JP) | 1993-05-12 | — | — | EP | disclosed |
| EP-0540296-A1 | Photographic processing agent | KONICA CORPORATION (JP) | 1993-05-05 | — | — | EP | disclosed |