SCHEMBL8629666

SCHEMBL8629666

CC(C)(C)c1cc(Oc2ccc(C#N)c(C#N)c2)c(Oc2ccc(C#N)c(C#N)c2)c(C(C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 17/20 0.42
CYP19A1 P11511 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8433560 0.83 KIF11 (0.42) ARCYP19A1
SCHEMBL9847772 0.82 AR (0.51) ARCYP19A1
SCHEMBL8626769 0.81 AR (0.45) ARCYP19A1
SCHEMBL9847760 0.81 AR (0.50) ARCYP19A1
SCHEMBL8431777 0.80 EPAS1 (0.42) ARCYP19A1
SCHEMBL9847768 0.78 AR (0.43) ARCYP19A1
SCHEMBL8623452 0.77 AR (0.53) ARCYP19A1
SCHEMBL9847755 0.77 AR (0.48) ARCYP19A1
SCHEMBL16541770 0.77 AR (0.42) ARCYP19A1
SCHEMBL8431775 0.77 POLB (0.43) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0757702-B1 POLY (IMIDE-ETHERS) DU PONT (US) 1998-07-01 EP disclosed
US-5675020-A CHEMICAL INTERMEDIATES FOR PREPARING AROMATIC POLYIMIDES THE UNIVERSITY OF LIVERPOOL (GB) 1997-10-07 US disclosed
US-5434240-A Films. fibers, encapsulation, thermoplastics THE UNIVERSITY OF LIVERPOOL (GB) 1995-07-18 US disclosed