Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 3/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 6/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630018 | 0.80 | ALDH1A1 (0.65) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5436576 | 0.79 | ALDH1A1 (0.63) | DAOCASP3SENP7SENP8SENP6 | |
| SCHEMBL24322069 | 0.79 | DAO (0.63) | DAOCASP3SENP7SENP8SENP6 | |
| SCHEMBL8633709 | 0.79 | ALDH1A1 (0.41) | CASP3SENP7ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8632472 | 0.78 | MAPT (0.39) | ALDH1A1LMNASNCASMN1; SMN2 | |
| SCHEMBL10274837 | 0.77 | DAO (0.61) | DAOCASP3SENP7SENP8SENP6 | |
| SCHEMBL10274827 | 0.73 | DAO (0.55) | DAOCASP3SENP7SENP8SENP6 | |
| SCHEMBL279422 | 0.72 | — | — | |
| SCHEMBL7368425 | 0.72 | DAO (0.71) | DAOCASP3SENP7SENP8SENP6 | |
| SCHEMBL5859674 | 0.72 | DAO (0.71) | DAOCASP3SENP7SENP8SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |