Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478345 | 1.00 | KMT2A (0.44) | KMT2ACYP1A2CYP2D6AKR1B1TP53 | |
| SCHEMBL8632970 | 0.86 | CYP1A2 (0.39) | KMT2ACYP1A2CYP2D6AKR1B1P2RX1 | |
| SCHEMBL8632967 | 0.86 | CYP1A2 (0.39) | KMT2ACYP1A2CYP2D6AKR1B1P2RX1 | |
| SCHEMBL6091601 | 0.82 | KMT2A (0.46) | KMT2ACYP1A2CYP2D6TP53LMNA | |
| SCHEMBL30996203 | 0.79 | CYP1A2 (0.55) | KMT2ACYP1A2CYP2D6TP53LMNA | |
| SCHEMBL1372846 | 0.79 | P2RX1 (0.49) | KMT2ACYP1A2CYP2D6TP53P2RX1 | |
| SCHEMBL5573253 | 0.79 | KMT2A (0.47) | KMT2ACYP1A2CYP2D6TP53LMNA | |
| SCHEMBL8909053 | 0.78 | KMT2A (0.40) | KMT2ACYP1A2CYP2D6TP53LMNA | |
| SCHEMBL7477677 | 0.78 | KMT2A (0.43) | KMT2ACYP1A2CYP2D6TP53LMNA | |
| SCHEMBL2180470 | 0.78 | KMT2A (0.46) | KMT2ACYP1A2CYP2D6TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600669-B1 | Photo reactive material | PILKINGTON PLC (GB) | 1998-06-24 | — | — | EP | disclosed |
| US-5446151-A | Photo reactive spiro-benzoxazine compounds | PILKINGTON PLC (GB) | 1995-08-29 | — | — | US | disclosed |
| EP-0600669-A1 | Photo reactive material | PILKINGTON PLC (GB) | 1994-06-08 | — | — | EP | disclosed |