Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28819177 | 0.89 | KMT2A (0.46) | KMT2AMAPTMEN1L3MBTL1CYP2D6 | |
| SCHEMBL6093583 | 0.79 | KMT2A (0.53) | KMT2AMAPTMEN1L3MBTL1CYP2D6 | |
| SCHEMBL8629800 | 0.78 | KMT2A (0.44) | KMT2AMAPTMEN1CYP2D6CYP1A2 | |
| SCHEMBL7478345 | 0.78 | KMT2A (0.44) | KMT2AMAPTMEN1CYP2D6CYP1A2 | |
| SCHEMBL6091601 | 0.78 | KMT2A (0.46) | KMT2AMAPTMEN1L3MBTL1CYP2D6 | |
| SCHEMBL10448669 | 0.77 | KMT2A (0.51) | KMT2AMAPTMEN1CYP2D6CYP1A2 | |
| SCHEMBL9868831 | 0.76 | KMT2A (0.50) | KMT2AMAPTMEN1CYP2D6CYP1A2 | |
| SCHEMBL19746373 | 0.76 | KMT2A (0.50) | KMT2AMAPTMEN1CYP2D6CYP1A2 | |
| SCHEMBL9736812 | 0.76 | KMT2A (0.50) | KMT2AMAPTMEN1CYP2D6CYP1A2 | |
| SCHEMBL8475420 | 0.76 | KMT2A (0.50) | KMT2AMAPTMEN1CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350009-B1 | Photochromic compound and photochromic composition | KUREHA CHEMICAL IND CO LTD (JP) | 1997-10-08 | — | — | EP | disclosed |