Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.61 |
| ▸ | PGR | P06401 | 4/20 | 0.61 |
| ▸ | SHBG | P04278 | 4/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.61 |
| ▸ | AR | P10275 | 3/20 | 0.61 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8629925 | 1.00 | LMNA (0.61) | LMNACYP3A4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8377385 | 0.90 | LMNA (0.64) | LMNACYP3A4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8377389 | 0.90 | LMNA (0.64) | LMNACYP3A4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4245550 | 0.86 | LMNA (0.66) | LMNACYP3A4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4245554 | 0.86 | LMNA (0.66) | LMNACYP3A4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6263252 | 0.85 | LMNA (0.73) | LMNACYP3A4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6263255 | 0.85 | LMNA (0.73) | LMNACYP3A4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8994192 | 0.82 | LMNA (0.68) | LMNACYP3A4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8994186 | 0.82 | LMNA (0.68) | LMNACYP3A4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8072118 | 0.81 | LMNA (0.61) | LMNACYP3A4ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760025-A | ADMINISTERING TESTOSTERONE 5A-REDUCTASE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 1998-06-02 | — | — | US | disclosed |
| US-5717088-A | REACTING WITH A CYANOPHOSPHATE IN THE PRESENCE OF AN ALKALI METAL CYANIDE | SANKYO COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| US-5698720-A | INTERMEDIATES FOR TESTOSTERONE 5-ALPHA-REDUCTASE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0567271-B1 | Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses | SANKYO CO (JP) | 1997-07-02 | — | — | EP | disclosed |
| EP-0725074-A2 | Compounds suitable for use as intermediates in the preparation of Androst-3,5-dien-3-carboxy derivatives | SANKYO COMPANY LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |
| US-5536714-A | Steroid derivatives for the treatment of prostatic hypertrophy their preparation and uses | SANKYO COMPANY, LIMITED (JP) | 1996-07-16 | — | — | US | disclosed |
| EP-0567271-A2 | Steroid derivatives for the treatment of prostatic hypertrophy, their preparation and uses | SANKYO COMPANY LIMITED (JP) | 1993-10-27 | — | — | EP | disclosed |