Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032510 | 0.87 | KMT2A (0.60) | KMT2AGAAMEN1MAPK1RECQL | |
| SCHEMBL15402702 | 0.85 | KMT2A (0.73) | KMT2AGAAMEN1MAPK1RECQL | |
| SCHEMBL21325585 | 0.85 | KCNH3 (0.53) | KMT2AGAAMEN1MAPK1RECQL | |
| SCHEMBL8039569 | 0.81 | KMT2A (0.61) | KMT2AGAAMEN1MAPK1RECQL | |
| SCHEMBL19670086 | 0.80 | CA1 (0.39) | KMT2AGAAMEN1MAPK1RECQL | |
| SCHEMBL13752164 | 0.80 | CA1 (0.43) | KMT2ASLC29A1KCNH3CA1CA2 | |
| SCHEMBL17018663 | 0.80 | RECQL (0.54) | KMT2AGAAMEN1MAPK1RECQL | |
| SCHEMBL16094829 | 0.78 | SLC29A1 (0.71) | KMT2AGAAMEN1MAPK1SLC29A1 | |
| SCHEMBL9102166 | 0.78 | CYP1A2 (0.53) | KMT2AMEN1KCNH3CA1CA2 | |
| SCHEMBL14380953 | 0.78 | KMT2A (0.52) | KMT2AGAAMEN1MAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632805-B1 | MELAMINE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | CANCER RES CAMPAIGN TECH (GB) | 1998-07-08 | — | — | EP | disclosed |
| US-5534625-A | 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVES; OVARIES | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 1996-07-09 | — | — | US | disclosed |