Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | DAO | P14920 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631463 | 0.83 | DAO (0.53) | ALDH1A1KDM4EDAOHDAC3HDAC4 | |
| SCHEMBL8633480 | 0.80 | DAO (0.56) | ALDH1A1SMN1; SMN2HTTMAPTKDM4E | |
| SCHEMBL27398463 | 0.74 | F2 (0.47) | ALDH1A1SMN1; SMN2MAPTKDM4EDAO | |
| SCHEMBL8629907 | 0.73 | KDM4E (0.37) | ALDH1A1HTTMAPTKDM4EDAO | |
| SCHEMBL8628998 | 0.73 | MAPT (0.43) | ALDH1A1SMN1; SMN2HTTMAPTKDM4E | |
| SCHEMBL7816128 | 0.72 | DAO (0.63) | ALDH1A1MAPTKDM4EDAOKMT2A | |
| SCHEMBL7815974 | 0.72 | DAO (0.42) | ALDH1A1SMN1; SMN2MAPTKDM4EDAO | |
| SCHEMBL8634456 | 0.71 | MAPT (0.41) | ALDH1A1SMN1; SMN2HTTMAPTKDM4E | |
| SCHEMBL13841460 | 0.71 | DPP4 (0.39) | ALDH1A1SMN1; SMN2HTTGSK3B | |
| SCHEMBL6375945 | 0.70 | KMT2A (0.53) | ALDH1A1SMN1; SMN2HTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |