Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2152835 | 0.85 | EPHX2 (0.48) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL21117782 | 0.85 | EPHX2 (0.48) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL2152834 | 0.85 | EPHX2 (0.48) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL10908977 | 0.84 | ALDH1A1 (0.47) | SLC6A2SLC6A4SLC6A3ALDH1A1NPC1 | |
| SCHEMBL11332243 | 0.83 | KMT2A (0.45) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL3712742 | 0.81 | SMN1; SMN2 (0.55) | MAPTTDP1L3MBTL1 | |
| SCHEMBL2635410 | 0.81 | SMN1; SMN2 (0.55) | MAPTTDP1L3MBTL1 | |
| SCHEMBL8174213 | 0.81 | SMN1; SMN2 (0.55) | MAPTTDP1L3MBTL1 | |
| SCHEMBL17648736 | 0.81 | TSHR (0.56) | ALDH1A1KDM4ELMNATSHR | |
| Hydrochloric Acid SCHEMBL1276908 | 0.80 | SMN1; SMN2 (0.54) | MAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719162-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-02-17 | — | — | US | disclosed |
| US-5719144-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-02-17 | — | — | US | disclosed |
| US-5665723-A | PIPERAZINE ISOINDOLE DERIVATIVES | MERCK & CO., INC. (US) | 1997-09-09 | — | — | US | disclosed |