Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GSR | P00390 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | GRM8 | O00222 | 1/20 | 0.54 |
| ▸ | GRM6 | O15303 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22598251 | 0.78 | GLO1 (0.58) | ALOX15BLMPMP22KMT2AGSR | |
| SCHEMBL11712204 | 0.75 | GSR (0.58) | ALOX15BLMPMP22KMT2AGSR | |
| SCHEMBL197385 | 0.75 | GSR (0.58) | ALOX15BLMPMP22KMT2AGSR | |
| SCHEMBL1768449 | 0.75 | GSR (0.58) | ALOX15BLMPMP22KMT2AGSR | |
| SCHEMBL3381963 | 0.75 | GSR (0.58) | ALOX15BLMPMP22KMT2AGSR | |
| SCHEMBL3382365 | 0.73 | GSR (0.56) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL411575 | 0.73 | KMT2A (1.00) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL7453 | 0.73 | KMT2A (1.00) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL7452 | 0.73 | KMT2A (1.00) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL411588 | 0.73 | KMT2A (1.00) | ALOX15BLMPMP22KMT2AGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854006-A | Gamma-glutamyl transpeptidase-specific antibody, prodrugs for the treatment of gamma-glutamyl transpeptidase-expressing tumors, and methods of administration thereof | THE UNIVERSITY OF VIRGINIA (US) | 1998-12-29 | — | — | US | disclosed |