Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 9/20 | 0.42 |
| ▸ | NOS1 | P29475 | 4/20 | 0.40 |
| ▸ | NOS3 | P29474 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | DHPS | P49366 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632146 | 0.70 | — | — | |
| SCHEMBL26318922 | 0.69 | DNM1 (0.39) | — | |
| SCHEMBL6643184 | 0.66 | MEN1 (0.70) | NOS2NOS1NOS3CYP1A2CYP3A4 | |
| SCHEMBL18072581 | 0.66 | MEN1 (0.70) | NOS2NOS1NOS3CYP1A2CYP3A4 | |
| SCHEMBL20961930 | 0.64 | — | — | |
| SCHEMBL3262584 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL3262631 | 0.62 | MEN1 (0.62) | NOS2NOS1NOS3CYP1A2CYP3A4 | |
| SCHEMBL24711284 | 0.61 | — | — | |
| SCHEMBL9749123 | 0.61 | — | — | |
| SCHEMBL15944943 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830917-A | L-N6 -(1-iminoethyl) lysine derivatives useful as nitric oxide synthase inhibitors | G. D. SEARLE & CO. (US) | 1998-11-03 | — | — | US | claimed |