Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863125 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL2213077 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| Diethylene Glycol Diisobutanoate SCHEMBL9561713 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL863288 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL7637824 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| Ethylene Glycol Diisobutanoate SCHEMBL843146 | 0.91 | TSHR (0.36) | ALDH1A1TSHRCHRNB2CHRNA4 | |
| SCHEMBL17976921 | 0.91 | MEN1 (0.50) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL6032764 | 0.91 | MEN1 (0.50) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL12390088 | 0.91 | HSD17B10 (0.43) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL16021805 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRTP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575276-B2 | Biomimetic compounds and synthetic methods therefor | KNC NER ACQUISITION SUB, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| US-20120078296-A1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | KNC NER ACQUISITION SUB, INC. (US) | 2012-03-29 | — | — | US | disclosed |