⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14566179 | 0.78 | — | — | |
| SCHEMBL28035286 | 0.76 | TSHR (0.46) | — | |
| SCHEMBL10915048 | 0.75 | — | — | |
| SCHEMBL28039850 | 0.75 | — | — | |
| SCHEMBL14339475 | 0.73 | TSHR (0.43) | — | |
| SCHEMBL1015618 | 0.73 | TSHR (0.65) | — | |
| SCHEMBL268400 | 0.73 | TSHR (0.59) | — | |
| SCHEMBL93462 | 0.73 | TSHR (0.84) | — | |
| SCHEMBL30604742 | 0.73 | TSHR (0.84) | — | |
| SCHEMBL35914 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610629-B1 | Curable organopolysiloxane compositions | SHINETSU CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5397814-A | Radiation-curable release coatings for self-adhesives | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-03-14 | — | — | US | disclosed |
| US-5391588-A | Polysiloxane with acryloxyorganosilyl end group, alpha-silyl ester compound, photoinitiator, curing catalyst | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0610629-A2 | Curable organopolysiloxane compositions | Shin-Etsu Chemical Co., Ltd. (JP) | 1994-08-17 | — | — | EP | disclosed |
| EP-0192683-B1 | LENS COMPOSITION, ARTICLE AND METHOD OF MANUFACTURE | PARAGON OPTICAL INC (US) | 1989-12-20 | — | — | EP | disclosed |
| EP-0184924-B1 | LENS COMPOSITION, ARTICLES AND METHOD OF MANUFACTURE | PARAGON OPTICAL INC (US) | 1988-11-30 | — | — | EP | disclosed |
| US-4769431-A | Polyacryloxyalkylsilanol lens composition, articles and method of manufacture | PARAGON OPTICAL INC. (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0192683-A4 | LENS COMPOSITION, ARTICLE AND METHOD OF MANUFACTURE. | PARAGON OPTICAL INC (US) | 1987-02-19 | — | — | EP | disclosed |
| EP-0192683-A1 | LENS COMPOSITION, ARTICLE AND METHOD OF MANUFACTURE. | PARAGON OPTICAL INC (US) | 1986-09-03 | — | — | EP | disclosed |
| EP-0184924-A2 | Lens composition, articles and method of manufacture | PARAGON OPTICAL INC (US) | 1986-06-18 | — | — | EP | disclosed |
| US-4582884-A | Lens composition, article and method of manufacture | PARAGON OPTICAL, INC. (US) | 1986-04-15 | — | — | US | disclosed |
| WO-1986001518-A1 | LENS COMPOSITION, ARTICLE AND METHOD OF MANUFACTURE | PARAGON OPTICAL, INC. (US) | 1986-03-13 | — | — | WO | disclosed |