SCHEMBL1015618

SCHEMBL1015618

C=CC(=O)OCCC[SiH2]O

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.65
ALDH1A1 P00352 4/20 0.65
CYP3A4 P08684 2/20 0.65
HPGD P15428 1/20 0.59
TP53 P04637 3/20 0.54
HIF1A Q16665 3/20 0.54
HSD17B10 Q99714 1/20 0.54
THRB P10828 2/20 0.41
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ATM Q13315 1/20 0.38
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL244114 0.82 TSHR (0.95) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL321925 0.82 TSHR (0.85) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8167341 0.82 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL6687708 0.80 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL13945622 0.80 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53
Ethylene SCHEMBL977945 0.80 TSHR (0.90) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9101988 0.80 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL20873747 0.80 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL322713 0.80 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL33725 0.80 TSHR (1.00) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1833905-B1 ELASTOMER COMPOSITION WHICH IS REINFORCED WITH A FUNCTIONALISED POLYVINYLAROMATIC FILLER MICHELIN & CIE (FR) 2013-08-07 EP claimed
US-8461269-B2 Elastomeric composition reinforced with a funtionalized non-aromatic vinyl polymer filler Micheln Recherche et Technique S.A. (CH) 2013-06-11 US claimed
US-20110021702-A1 FUNCTIONALIZED VINYL POLYMER NANOPARTICLES MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2011-01-27 US claimed
US-7820771-B2 copolymer of styrene, ethylvinylbenzene, divinylbenzene and trimethoxysilylpropyl(meth)acrylate, being in the form of nanobeads as reinforcing filler; tires or rubber semi-finished products intended for these tires MICHELIN RECHERCHE ET TECHNIQUE S. A. (CH) 2010-10-26 US claimed
EP-1838765-B1 FUNCTIOANALISED POLYVINYLAROMATIC NANOPARTICLES MICHELIN RECH TECH (CH) 2010-08-04 EP claimed
US-20100022714-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNTIONALIZED NON-AROMATIC VINYL POLYMER FILLER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2010-01-28 US claimed
US-20090270558-A1 Functionalized Polyvinylaromatic Nanoparticles MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2009-10-29 US claimed
US-20080132644-A1 copolymer of styrene, ethylvinylbenzene, divinylbenzene and trimethoxysilylpropyl(meth)acrylate, being in the form of nanobeads as reinforcing filler; tires or rubber semi-finished products intended for these tires MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2008-06-05 US claimed
US-12630654-B2 Emulsion particle-containing aqueous dispersion NIPPON SHOKUBAI CO., LTD. (JP) 2026-05-19 US disclosed
EP-4726008-A1 AGENT FOR IMPARTING HYDROPHILICITY-SUSTAINING EFFECT AND/OR WATER SLIDING PROPERTIES Nippon Shokubai Co., Ltd. (JP) 2026-04-15 EP disclosed
US-12590215-B2 Ink for ink-jet textile printing, method for producing printed matter using said ink, and article with adhered image NIPPON SHOKUBAI CO., LTD. (JP) 2026-03-31 US disclosed
US-12503614-B2 Resin emulsion for water-based ink NIPPON SHOKUBAI CO., LTD. (JP) 2025-12-23 US disclosed
US-12473456-B2 Aqueous dispersion, production method therefor, coating composition, and coating film NIPPON SHOKUBAI CO., LTD. (JP) 2025-11-18 US disclosed
WO-2025053280-A1 OPTICAL WAVEGUIDE AND OPTICAL MEMBER HAVING OPTICAL WAVEGUIDE 三菱ケミカル株式会社 2025-03-13 WO disclosed
CN-108026405-B Resin emulsion for paint 株式会社日本触媒 2020-12-01 CN disclosed
WO-2020085260-A1 AQUEOUS RESIN COMPOSITION, PRODUCTION METHOD FOR AQUEOUS RESIN COMPOSITION, AND USE FOR AQUEOUS RESIN COMPOSITION 株式会社日本触媒 2020-04-30 WO disclosed
WO-2020085263-A1 AQUEOUS DISPERSION, PRODUCTION METHOD FOR AQUEOUS DISPERSION, AND USE FOR AQUEOUS DISPERSION 株式会社日本触媒 2020-04-30 WO disclosed
US-8461269-B2 Elastomeric composition reinforced with a funtionalized non-aromatic vinyl polymer filler Micheln Recherche et Technique S.A. (CH) 2013-06-11 US disclosed
US-20120322005-A1 PARTICLES AND METHOD FOR PRODUCING THE SAME, TONER AND METHOD FOR PRODUCING THE SAME, DEVELOPER, PROCESS CARTRIDGE, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-20100022714-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNTIONALIZED NON-AROMATIC VINYL POLYMER FILLER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630654-B2 Emulsion particle-containing aqueous dispersion CLTB, CLTA, APOB TSHR 3515/4885ALDH1A1 559/4885CYP3A4 1827/4885
US-12590215-B2 Ink for ink-jet textile printing, method for producing printed matter using said ink, and article with adhered image PSD, EPHA7, EED TSHR 4240/4885ALDH1A1 324/4885CYP3A4 1325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.