Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19158147 | 0.83 | MAPT (0.49) | POLBAOC3MEN1KMT2A | |
| SCHEMBL23160468 | 0.81 | AOC3 (0.49) | AOC3MEN1KMT2ASLC2A1RPS6KA2 | |
| SCHEMBL2895679 | 0.80 | CHRM5 (0.39) | POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13930466 | 0.79 | SLC2A1 (0.47) | AOC3SLC2A1RPS6KA2CA1CA2 | |
| SCHEMBL8629892 | 0.77 | KDM4E (0.44) | POLBAOC3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16076001 | 0.77 | AOC3 (0.49) | AOC3MEN1KMT2ASLC2A1RPS6KA2 | |
| SCHEMBL12637623 | 0.75 | TSHR (0.53) | POLBMEN1KMT2ACDK4SMN1; SMN2 | |
| SCHEMBL8633500 | 0.75 | CNR2 (0.47) | POLBMEN1KMT2ANPC1 | |
| SCHEMBL11422003 | 0.73 | MAPT (0.44) | AOC3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL6868406 | 0.73 | RPS6KA2 (0.45) | AOC3SLC2A1RPS6KA2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761214-A2 | N,N-disubstituted anilines or alkylamines as singlet oxygen quenchers, topical compositions comprising them | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |