Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633500 | 0.94 | CNR2 (0.47) | KDM4EMAPK1TDP1CNR2CASR | |
| SCHEMBL8632573 | 0.87 | KDM4E (0.39) | KDM4EMAPK1TDP1CNR2POLB | |
| SCHEMBL8628573 | 0.85 | MAPT (0.43) | KDM4EMAPK1TDP1CNR2POLB | |
| SCHEMBL8628766 | 0.84 | CNR2 (0.48) | KDM4EMAPK1TDP1CNR2PPARG | |
| SCHEMBL1573445 | 0.81 | CNR2 (0.47) | MAPK1CNR2PPARGSMN1; SMN2AOC3 | |
| SCHEMBL8628545 | 0.81 | KDM4E (0.36) | KDM4EMAPK1TDP1POLBMEN1 | |
| SCHEMBL8631317 | 0.77 | POLB (0.46) | POLBMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL24359339 | 0.76 | CNR2 (0.52) | MAPK1CNR2PPARGSMN1; SMN2AOC3 | |
| SCHEMBL22340749 | 0.74 | CNR2 (0.54) | CNR2NR1H2NR1H3 | |
| SCHEMBL8629617 | 0.74 | ALDH1A1 (0.41) | KDM4EPOLBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709816-A | N,N-DISUBSTITUTED ANILINE COMPOUNDS | KAO CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761214-A2 | N,N-disubstituted anilines or alkylamines as singlet oxygen quenchers, topical compositions comprising them | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |