Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.78 |
| ▸ | MAOA | P21397 | 1/20 | 0.74 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MC4R | P32245 | 1/20 | 0.56 |
| ▸ | MC5R | P33032 | 1/20 | 0.56 |
| ▸ | MC3R | P41968 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8645237 | 0.98 | CHRM2 (0.75) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL10938227 | 0.96 | CHRM2 (0.77) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL16151775 | 0.96 | CHRM2 (0.70) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL9192642 | 0.96 | CHRM2 (0.70) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29778302 | 0.94 | CHRM2 (0.68) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL2761312 | 0.94 | CHRM2 (0.74) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29778293 | 0.94 | CHRM2 (0.68) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL8643581 | 0.94 | CHRM2 (0.81) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL12523230 | 0.94 | CHRM2 (0.68) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL21799882 | 0.92 | MAOA (0.80) | CHRM2MAOASIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719193-A | Method of potentiating cell-mediated immunity utilizing polyamine derivatives | MERRELL PHARMACEUTICALS, INC. (US) | 1998-02-17 | — | — | US | claimed |
| US-5753714-A | ANTIPROTOZOA AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1998-05-19 | — | — | US | disclosed |
| US-5719193-A | Method of potentiating cell-mediated immunity utilizing polyamine derivatives | MERRELL PHARMACEUTICALS, INC. (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0277635-A2 | Novel polyamine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-10 | — | — | EP | disclosed |