Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777659 | 0.93 | PTGS2 (0.47) | PTGS2ALPGSMN1; SMN2PTGS1MEN1 | |
| SCHEMBL7780128 | 0.92 | PTGS2 (0.47) | PTGS2PI4KBPTGS1 | |
| SCHEMBL7777879 | 0.90 | PTGS2 (0.49) | PTGS2PI4KBPTGS1 | |
| SCHEMBL8181641 | 0.90 | PTGS2 (0.52) | PTGS2PI4KBPTGS1 | |
| SCHEMBL7778215 | 0.90 | PTGS2 (0.54) | PTGS2PI4KBPTGS1 | |
| SCHEMBL7779842 | 0.87 | PTGS2 (0.46) | PTGS2PI4KBPTGS1KDM4EKMT2A | |
| SCHEMBL7779889 | 0.87 | PTGS2 (0.46) | PTGS2PI4KBPTGS1 | |
| SCHEMBL7779398 | 0.85 | PTGS2 (0.48) | PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL7777989 | 0.84 | PTGS2 (0.54) | PTGS2PTGS1NPSR1 | |
| SCHEMBL7779812 | 0.84 | PTGS2 (0.56) | PTGS2PI4KBPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |