SCHEMBL8632043

SCHEMBL8632043

CCCCCCC(C)OS(C)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.44
FAAH O00519 5/20 0.42
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
ALDH1A1 P00352 2/20 0.41
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
ADH7 P40394 1/20 0.38
OPRM1 P35372 1/20 0.38
SMPD1 P17405 3/20 0.37
ACE2 Q9BYF1 1/20 0.37
CA2 P00918 1/20 0.37
GPR84 Q9NQS5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8843279 1.00 TP53 (0.44) TP53FAAHCNR1CNR2ALDH1A1
SCHEMBL8843258 1.00 TP53 (0.44) TP53FAAHCNR1CNR2ALDH1A1
SCHEMBL22263512 1.00 TP53 (0.44) TP53FAAHCNR1CNR2ALDH1A1
SCHEMBL1033067 1.00 TP53 (0.44) TP53FAAHCNR1CNR2ALDH1A1
SCHEMBL14185392 1.00 TP53 (0.44) TP53FAAHCNR1CNR2ALDH1A1
SCHEMBL8843220 1.00 TP53 (0.44) TP53FAAHCNR1CNR2ALDH1A1
SCHEMBL8844066 1.00 TP53 (0.44) TP53FAAHCNR1CNR2ALDH1A1
SCHEMBL10838919 0.98 TP53 (0.45) TP53FAAHCNR1CNR2ALDH1A1
SCHEMBL4438455 0.91 ALDH1A1 (0.44) TP53FAAHCNR1CNR2ALDH1A1
SCHEMBL905471 0.91 ALDH1A1 (0.44) TP53FAAHCNR1CNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723670-A REACTION OF AROMATIC AMINE WITH HALIDE AND SULFONATE DERIVATIVE BAYER CORPORATION (US) 1998-03-03 US claimed
WO-2024017178-A1 SUBSTITUTED HYDANTOIN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS AVITAR BIOSCIENCES, INC. (CN) 2024-01-25 WO disclosed
CN-115947681-A Modulators of integrated stress pathways 卡里科生命科学有限责任公司 2023-04-11 CN disclosed
CN-109641844-B Modulators of integrated stress pathways 卡里科生命科学有限责任公司 2022-11-01 CN disclosed
US-9240614-B2 Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES, LTD. (JP) 2016-01-19 US disclosed
CN-102271517-B Oxidized lipid compounds and uses thereof VASCULAR BIOGENICS LTD 2015-04-08 CN disclosed
US-20130071733-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES, LTD. (JP) 2013-03-21 US disclosed
US-5723670-A REACTION OF AROMATIC AMINE WITH HALIDE AND SULFONATE DERIVATIVE BAYER CORPORATION (US) 1998-03-03 US disclosed
US-5476646-A Gastrointestinal tract STERLING WINTHROP INC. (US) 1995-12-19 US disclosed
US-5443814-A X-ray contrast compositions containing iodophenoxyalkanes and cellulose derivatives STERLING WINTHROP, INC. 1995-08-22 US disclosed
US-4576964-A ANALGESICS, ANTIEMETICS PFIZER INC. (US) 1986-03-18 US disclosed
US-4476131-A ANTIEMETICS, ANALGESICS PFIZER INC. (US) 1984-10-09 US disclosed
US-4473704-A ANALGESICS, ANTIEMETICS PFIZER INC. (US) 1984-09-25 US disclosed
EP-0090526-A1 Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta(1)phenanthrenes, decahydro-1H-pyrido(1,2-f)phenanthridines and decahydropyrrolo(1,2-f)phenanthridines as CNS agents PFIZER INC. (US) 1983-10-05 EP disclosed
EP-0090516-A1 Substituted hexahydropyrrolo(1,2-a)-quinoline, hexahydro-1H-pyrido(1,2-a)-quinoline, hexahydrobenzo(3)indene and octahydrophenanthrene CNS agents PFIZER INC. (US) 1983-10-05 EP disclosed
US-4405626-A TRANQUILIZERS, HYPOTENSIVE AGENTS; DIURETICS; VISION DEFECTS PFIZER INC. (US) 1983-09-20 US disclosed
US-4400385-A TRANQUILIZERS, HYPOTENSIVE AGENTS; DIURETICS; VISION DEFECTS PFIZER INC. (US) 1983-08-23 US disclosed
US-4380542-A ANALGESICS, TRANQUILIZERS PFIZER (US) 1983-04-19 US disclosed
US-4340737-A CNS AGENTS, HYPOTENSIVES, DIURETICS AND AGENTS FOR TREATMENT OF GLAUCOMA PFIZER INC. (US) 1982-07-20 US disclosed
US-4260764-A ANALGESICS, TRANQUILIZERS PFIZER INC. (US) 1981-04-07 US disclosed