Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7333194 | 0.95 | KCNH2 (0.74) | KCNH2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7332936 | 0.90 | KCNH2 (0.67) | KCNH2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7333287 | 0.89 | KCNH2 (0.67) | KCNH2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7424137 | 0.89 | KCNH2 (0.66) | KCNH2MAPTSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7334757 | 0.89 | KCNH2 (0.66) | KCNH2MAPTSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7358074 | 0.88 | KCNH2 (0.65) | KCNH2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7334434 | 0.87 | KCNH2 (0.91) | KCNH2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7356528 | 0.85 | KCNH2 (0.60) | KCNH2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7425124 | 0.85 | KCNH2 (0.73) | KCNH2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7327022 | 0.85 | KCNH2 (0.56) | KCNH2MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852142-A1 | Diamines in the treatment of arrhythmia | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1998-07-08 | — | — | EP | disclosed |