Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779315 | 0.89 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL7772800 | 0.89 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL7779834 | 0.89 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL7777679 | 0.88 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL7773338 | 0.85 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL7780680 | 0.85 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL7780601 | 0.82 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL7779957 | 0.80 | CSNK1D (0.65) | PTGS2PTGS1 | |
| SCHEMBL7779948 | 0.78 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL7772843 | 0.78 | CA9 (0.47) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |
| US-5486534-A | 3,4-substituted pyrazoles for the treatment of inflammation | G. D. SEARLE & CO. (US) | 1996-01-23 | — | — | US | disclosed |