Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16753020 | 0.84 | EPHX2 (0.57) | EPHX2KCNH2ALDH1A1MAPTKDM4E | |
| SCHEMBL10878735 | 0.84 | EPHX2 (0.57) | EPHX2KCNH2ALDH1A1MAPTKDM4E | |
| SCHEMBL3924849 | 0.84 | EPHX2 (0.57) | EPHX2KCNH2ALDH1A1MAPTKDM4E | |
| SCHEMBL30889345 | 0.84 | EPHX2 (0.57) | EPHX2KCNH2ALDH1A1MAPTKDM4E | |
| SCHEMBL8921829 | 0.84 | EPHX2 (0.57) | EPHX2KCNH2ALDH1A1MAPTKDM4E | |
| SCHEMBL11130551 | 0.84 | ACHE (0.53) | EPHX2MAPTALOX5PTGS1PTGS2 | |
| SCHEMBL3394938 | 0.82 | EPHX2 (0.54) | EPHX2KCNH2ALDH1A1MAPTKDM4E | |
| SCHEMBL20860694 | 0.81 | EPHX2 (0.54) | EPHX2KCNH2ALDH1A1MAPTKDM4E | |
| SCHEMBL12194495 | 0.81 | EPHX2 (0.54) | EPHX2KCNH2ALDH1A1MAPTKDM4E | |
| SCHEMBL20877601 | 0.79 | EPHX2 (0.53) | EPHX2KCNH2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755671-B1 | DERMATOLOGIC PREPARATION | KAO CORP (JP) | 1998-07-08 | — | — | EP | disclosed |
| EP-0755671-A1 | DERMATOLOGIC PREPARATION | Kao Corporation (JP) | 1997-01-29 | — | — | EP | disclosed |