Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8631648 | 0.90 | AR (0.41) | GAAARMAPTALDH1A1MEN1 | |
| SCHEMBL8631394 | 0.90 | AR (0.43) | GAAARMAPTALDH1A1KDM4E | |
| SCHEMBL8630543 | 0.90 | SMN1; SMN2 (0.46) | ARMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL8633612 | 0.87 | GAA (0.45) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL8633054 | 0.87 | SMN1; SMN2 (0.41) | GAAARMAPTALDH1A1KDM4E | |
| SCHEMBL8635630 | 0.87 | AR (0.40) | GAAARMAPTALDH1A1KDM4E | |
| SCHEMBL8631588 | 0.85 | GAA (0.47) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL8631464 | 0.84 | PI4KB (0.40) | MAPTPTGS2 | |
| SCHEMBL8635051 | 0.82 | SMN1; SMN2 (0.42) | ARMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8630518 | 0.81 | AR (0.43) | ARMAPTALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756530-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G. D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |