Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410806 | 0.76 | MAPT (0.51) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL9413995 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTTDP1HTTNPC1 | |
| SCHEMBL11771158 | 0.72 | SMN1; SMN2 (0.40) | ALDH1A1TDP1NPSR1LMNAPKM | |
| SCHEMBL7763885 | 0.69 | ALDH1A1 (0.44) | ALDH1A1MAPTTDP1HTTNPC1 | |
| SCHEMBL7763858 | 0.68 | CYP3A4 (0.45) | ALDH1A1MAPTTDP1HTTNPC1 | |
| SCHEMBL416938 | 0.68 | HPGD (0.48) | ALDH1A1MAPTTDP1HTTLMNA | |
| SCHEMBL15281393 | 0.66 | ALDH1A1 (1.00) | ALDH1A1MAPTTDP1HTTNPC1 | |
| SCHEMBL5391863 | 0.66 | CYP3A4 (0.46) | ALDH1A1MAPTTDP1HTTNPC1 | |
| SCHEMBL7765236 | 0.66 | ALDH1A1 (0.42) | ALDH1A1MAPTTDP1HTTNPC1 | |
| SCHEMBL5391867 | 0.65 | CYP3A4 (0.45) | ALDH1A1MAPTTDP1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824528-A1 | SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES WITH ARYLOXY OR ARYLTHIO SUBSTITUENTS | BAYER AG (DE) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035680-A1 | SULPHONYLAMINO(THIO)CARBONYLTRIAZOLIN(THI)ONES WITH ARYLOXY OR ARYLTHIO SUBSTITUENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-14 | — | — | WO | disclosed |