SCHEMBL8632293

SCHEMBL8632293

CC(C)Cc1ccc(-c2ccccc2CC(C)C)cc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
EDNRB P24530 1/20 0.44
EDNRA P25101 1/20 0.44
GABRA1 P14867 2/20 0.44
GABRB2 P47870 2/20 0.44
S1PR1 P21453 1/20 0.43
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8121859 0.89 S1PR1 (0.42) KMT2AEDNRBEDNRAGABRA1GABRB2
SCHEMBL8123369 0.89 PDCD1 (0.44) KMT2AEDNRBEDNRAGABRA1GABRB2
SCHEMBL9394493 0.89 KMT2A (0.47) KMT2AEDNRBEDNRAGABRA1GABRB2
SCHEMBL8755224 0.89 PPARA (0.54) KMT2AEDNRBEDNRAS1PR1PPARG
SCHEMBL11731370 0.87 KMT2A (0.42) KMT2AEDNRBEDNRAGABRA1GABRB2
SCHEMBL4630258 0.86 KMT2A (0.60) KMT2AGABRA1GABRB2
SCHEMBL13873005 0.83 KMT2A (0.44) KMT2AGABRA1GABRB2
SCHEMBL8492143 0.83 GABRA1 (0.52) KMT2AGABRA1GABRB2PPARGPPARA
SCHEMBL12585106 0.83 KMT2A (0.44) KMT2AGABRA1GABRB2
SCHEMBL9394917 0.83 PPARA (0.41) KMT2AEDNRBEDNRAS1PR1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0504541-B1 Improved catalytic process for selective alkylation of aromatic hydrocarbons SOLUTIA EUROP NV SA (BE) 1998-07-22 EP disclosed
US-5233111-A CATALYTIC PROCESS FOR SELECTIVE ALKYLATION OF AROMATIC HYDROCARBONS MONSANTO COMPANY (US) 1993-08-03 US disclosed
EP-0504541-A1 Improved catalytic process for selective alkylation of aromatic hydrocarbons MONSANTO EUROPE S.A./N.V. (BE) 1992-09-23 EP disclosed