Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632494 | 1.00 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTPSMB5 | |
| SCHEMBL8488756 | 0.92 | MMP1 (0.42) | MEN1KMT2ALMNAMAPTPSMB5 | |
| SCHEMBL8502085 | 0.92 | FNTA (0.36) | MEN1KMT2ALMNAMAPTPSMB5 | |
| SCHEMBL8497542 | 0.91 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTPSMB5 | |
| SCHEMBL8497546 | 0.91 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTPSMB5 | |
| SCHEMBL8502192 | 0.90 | FNTA (0.37) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL8498192 | 0.89 | FNTA (0.37) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL8493907 | 0.89 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTPSMB5 | |
| SCHEMBL8493902 | 0.89 | MEN1 (0.41) | MEN1KMT2ALMNAMAPTPSMB5 | |
| SCHEMBL8492986 | 0.88 | FNTA (0.39) | MEN1KMT2ALMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999012912-A1 | THIOUREA DERIVATIVES OR NON-TOXIC SALTS THEREOF FOR INHIBITNG RAS-TRANSFORMED CELL GROWTH | YUHAN CORPORATION (KR) | 1999-03-18 | — | — | WO | disclosed |