SCHEMBL8632506

SCHEMBL8632506

CC(C)(C)OC(=O)NCCCNCC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.67
MAOB P27338 1/20 0.67
MEN1 O00255 1/20 0.58
GAA P10253 1/20 0.58
KMT2A Q03164 1/20 0.58
TDP1 Q9NUW8 1/20 0.57
CA1 P00915 8/20 0.48
CA2 P00918 8/20 0.48
CA12 O43570 6/20 0.48
CA9 Q16790 6/20 0.48
STK17B O94768 1/20 0.43
STK17A Q9UEE5 1/20 0.43
EPHX1 P07099 1/20 0.41
HTT P42858 1/20 0.40
CCNC P24863 1/20 0.39
CDK8 P49336 1/20 0.39
IDO1 P14902 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14562406 0.97 MAOA (0.71) MAOAMAOBMEN1GAAKMT2A
SCHEMBL25354673 0.95 MAOA (0.74) MAOAMAOBMEN1GAAKMT2A
SCHEMBL2153073 0.89 MAOA (0.57) MAOAMAOBMEN1GAAKMT2A
SCHEMBL7624292 0.89 MAOA (0.57) MAOAMAOBMEN1GAAKMT2A
SCHEMBL31526371 0.88 MEN1 (0.57) MAOAMAOBMEN1GAAKMT2A
SCHEMBL1557057 0.87 TDP1 (0.67) MAOAMAOBMEN1GAAKMT2A
SCHEMBL18347560 0.85 TDP1 (0.70) MAOAMAOBMEN1GAAKMT2A
SCHEMBL1298855 0.85 TDP1 (0.70) MAOAMAOBMEN1GAAKMT2A
SCHEMBL569251 0.85 TDP1 (0.74) MAOAMAOBMEN1GAAKMT2A
Bromide SCHEMBL25375155 0.85 MAOA (0.65) MAOAMAOBMEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105377875-B Peptidomimetic affinity ligands for purifying antibodies or antibody fragments 斯蒂法诺·梅内加蒂 2019-11-26 CN disclosed
US-10065988-B2 Peptoid affinity ligands STEFANO MENEGATTI (US) 2018-09-04 US disclosed
EP-3004136-B1 PEPTOID AFFINITY LIGANDS FOR THE PURIFICATION OF ANTIBODIES OR ANTIBODY FRAGMENTS MENEGATTI STEFANO (US) 2017-04-12 EP disclosed
EP-3004136-A1 PEPTOID AFFINITY LIGANDS FOR THE PURIFICATION OF ANTIBODIES OR ANTIBODY FRAGMENTS Menegatti, Stefano (US) 2016-04-13 EP disclosed
US-20160075734-A1 PEPTOID AFFINITY LIGANDS LIGATRAP TECHNOLOGIES, LLC 2016-03-17 US disclosed
WO-2014194073-A1 PEPTOID AFFINITY LIGANDS FOR THE PURIFICATION OF ANTIBODIES OR ANTIBODY FRAGMENTS MENEGATTI STEFANO (US) 2014-12-04 WO disclosed
EP-0680468-B1 SUBSTITUTED AMINO COMPOUNDS, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THROMBOCYTE AGGREGATION HOECHST AG (DE) 1998-06-24 EP disclosed
US-5681838-A ALSO FOR SUPPRESSING CANCER CELL METASTASES AND BINDING OF OSTEOCLASTS TO BONE SURFACES HOECHST AKTIENGESELLSCHAFT (DE) 1997-10-28 US disclosed
US-5668290-A CEPHALOSPORIN DERIVATIVES AS BACTERICIDES FOR GRAMPOSITIVE BACTERIA RESISTANT TO METHICILLIN BRISTOL-MYERS SQUIBB COMPANY (US) 1997-09-16 US disclosed
US-5620969-A BACTERICIDES BRISTOL-MYERS SQUIBB COMPANY (US) 1997-04-15 US disclosed
EP-0680468-A1 SUBSTITUTED AMINO COMPOUNDS, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THROMBOCYTE AGGREGATION HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160075734-A1 PEPTOID AFFINITY LIGANDS SLC7A1, CD74, CD2BP2 MAOA 4736/4885MAOB 4742/4885MEN1 2646/4885
US-10065988-B2 Peptoid affinity ligands SLC7A1, CD74, CD2BP2 MAOA 4736/4885MAOB 4742/4885MEN1 2646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.