Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 8/20 | 0.48 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630231 | 1.00 | P2RX4 (0.48) | P2RX4NISCHMAPTCTDSP1ALDH1A1 | |
| SCHEMBL7819783 | 0.85 | MAPT (0.52) | NISCHMAPTCTDSP1ALDH1A1PKM | |
| SCHEMBL8630646 | 0.84 | NISCH (0.47) | P2RX4NISCHMAPTALDH1A1PKM | |
| SCHEMBL8630509 | 0.84 | NISCH (0.47) | P2RX4NISCHMAPTALDH1A1PKM | |
| SCHEMBL8627514 | 0.84 | NISCH (0.47) | P2RX4NISCHMAPTALDH1A1PKM | |
| SCHEMBL8632329 | 0.79 | TSHR (0.52) | MAPTALDH1A1HSD17B10 | |
| SCHEMBL16362032 | 0.75 | NISCH (0.52) | P2RX4NISCHMAPTALDH1A1KDM4E | |
| SCHEMBL8628468 | 0.74 | NISCH (0.40) | P2RX4NISCHMAPT | |
| SCHEMBL3072283 | 0.72 | P2RX4 (0.60) | P2RX4ALDH1A1 | |
| SCHEMBL30972513 | 0.72 | MAPT (0.49) | MAPTALDH1A1PKMKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824652-A | IMMUNOSTIMULANTS, ANTITUMOR AGENTS | UNIVERZA V LJUBLJANI, FAKULTETA ZA NARAVOSLOVJE IN TECHNOLOGIJO, ODDELEK ZA FARMACIJO (SI) | 1998-10-20 | — | — | US | disclosed |
| EP-0695308-B1 | NOVEL HETEROCYCLIC ACYLDIPEPTIDES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UNIV LJUBLJANI (SI) | 1998-07-01 | — | — | EP | disclosed |
| EP-0695308-A1 | NOVEL HETEROCYCLIC ACYLDIPEPTIDES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UNIVERZA V LJUBLJANI, FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, ODDELEK ZA FARMACIJO (SI) | 1996-02-07 | — | — | EP | disclosed |
| WO-1994024152-A1 | NOVEL HETEROCYCLIC ACYLDIPEPTIDES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UNIVERZA V LJUBLJANI, FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, ODDELEK ZA FARMACIJO (SI) | 1994-10-27 | — | — | WO | disclosed |