Cyclohexene

Cyclohexene

SCHEMBL8632745

C1=CCCCC1.c1ccc2c(c1)CCC2

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.63
MAOB P27338 4/20 0.44
MAOA P21397 3/20 0.44
CYP2A6 P11509 2/20 0.44
HTR2C P28335 1/20 0.42
MAPT P10636 1/20 0.40
DRD4 P21917 2/20 0.38
PNMT P11086 1/20 0.37
CD44 P16070 1/20 0.37
DRD2 P14416 1/20 0.36
DRD1 P21728 1/20 0.36
DRD5 P21918 1/20 0.36
DRD3 P35462 1/20 0.36
HPGD P15428 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
G6PC1 P35575 1/20 0.35
ALDH1A1 P00352 1/20 0.35
BCL2L1 Q07817 1/20 0.34
BAD Q92934 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30405051 0.94 TSHR (0.72) TSHRMAOBMAOACYP2A6HTR2C
SCHEMBL30405623 0.92 TSHR (0.68) TSHRMAOBMAOACYP2A6HTR2C
Cyclohexene SCHEMBL28700166 0.92 TSHR (0.68) TSHRMAOBMAOACYP2A6HTR2C
SCHEMBL30405435 0.92 TSHR (0.68) TSHRMAOBMAOACYP2A6HTR2C
SCHEMBL30877931 0.90 TSHR (0.65) TSHRMAOBMAOACYP2A6HTR2C
SCHEMBL30877942 0.87 TSHR (0.62) TSHRMAOBMAOACYP2A6HTR2C
SCHEMBL30492078 0.86 TSHR (0.60) TSHRMAOBMAOACYP2A6HTR2C
SCHEMBL9662 0.85
SCHEMBL451157 0.85 TSHR (0.86) TSHRMAOBMAOACYP2A6HTR2C
SCHEMBL29354295 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0598241-B1 Lithographic printing material FUJI PHOTO FILM CO LTD (JP) 1998-02-04 EP disclosed
US-5387483-A Developer containing silver halide solvent and hydroquinone; has pH up to 11.8 FUJI PHOTO FILM CO., LTD. (JP) 1995-02-07 US disclosed
EP-0601600-A2 Processing of lithographic printing material and developer used therein FUJI PHOTO FILM CO., LTD. (JP) 1994-06-15 EP disclosed
EP-0598241-A1 Lithographic printing material FUJI PHOTO FILM CO., LTD. (JP) 1994-05-25 EP disclosed