Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.86 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | CD44 | P16070 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3057782 | 1.00 | TSHR (0.86) | TSHRMAOBMAOACYP2A6HTR2C | |
| SCHEMBL9662 | 1.00 | — | — | |
| SCHEMBL29354295 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL6332955 | 0.96 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| Bromide SCHEMBL9504217 | 0.96 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| Methane SCHEMBL19946467 | 0.96 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| SCHEMBL8676208 | 0.96 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| SCHEMBL6277308 | 0.96 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| Ammonia Solution, Strong SCHEMBL1151087 | 0.96 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C | |
| Water SCHEMBL7121211 | 0.96 | TSHR (0.80) | TSHRMAOBMAOACYP2A6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367908-B1 | FUEL COMPOSITION FOR USE IN GASOLINE ENGINES | SHELL INT RESEARCH (NL) | 2013-02-20 | — | — | EP | claimed |
| EP-3475391-A1 | PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT AROMATICS (BTX) AND BIOFUELS FROM BIOMASS | Biobtx B.V. (NL) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017222380-A1 | PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT AROMATICS (BTX) AND BIOFUELS FROM BIOMASS | BIOBTX B.V. (NL) | 2017-12-28 | — | — | WO | disclosed |
| CN-107001783-A | Platable resin composition | 沙特基础工业全球技术公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-104718238-B | Dihydroxy aromatic compounds is prepared by the alcoholysis compositions containing Merlon | 沙特基础工业公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-102933236-B | Pyrrolobenzodiazepines and conjugates thereof | SPIROGEN LTD. (CH) | 2014-10-08 | — | — | CN | disclosed |
| US-20140225101-A1 | Organic Semiconductor Composition And Organic Transistor | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2014-08-14 | — | — | US | disclosed |
| EP-2367907-B1 | FUEL COMPOSITION FOR USE IN GASOLINE ENGINES | SHELL INT RESEARCH (NL) | 2013-04-24 | — | — | EP | disclosed |
| CN-102933236-A | Pyrrolobenzodiazepines and conjugates thereof | SPIROGEN LTD | 2013-02-13 | — | — | CN | disclosed |
| US-20120101316-A1 | METHOD FOR THE PREPARATION OF A FUEL COMPOSITION FOR USE IN GASOLINE ENGINES AND BLENDING COMPONENT | SHELL OIL COMPANY | 2012-04-26 | — | — | US | disclosed |
| EP-2367908-A1 | FUEL COMPOSITION FOR USE IN GASOLINE ENGINES | Shell Internationale Research Maatschappij B.V. (NL) | 2011-09-28 | — | — | EP | disclosed |
| US-7989445-B2 | Thienopyrimidone compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-08-02 | — | — | US | disclosed |
| US-20110105572-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | TOPOTARGET UK LIMITED (GB) | 2011-05-05 | — | — | US | disclosed |
| US-7935836-B2 | Compounds comprising a linear series of five fused carbon rings, and preparation thereof | FALLIS ALEXANDER GRAHAM | 2011-05-03 | — | — | US | disclosed |
| EP-1432669-B1 | 4-(C2-6 ALKOXY)-SUBSTITUTED CHALCONES AS THERAPEUTIC AGENTS | SPEAR THERAPEUTICS LTD (GB) | 2011-03-23 | — | — | EP | disclosed |
| EP-2292593-A2 | Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors | TopoTarget UK Limited (GB) | 2011-03-09 | — | — | EP | disclosed |
| US-7880020-B2 | e.g trichlorostatin A; antiproliferative agent; for treating cancer and psoriasis | TOPOTARGET UK LIMITED (GB) | 2011-02-01 | — | — | US | disclosed |
| US-20100249197-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | TOPOTARGET UK LIMITED (GB) | 2010-09-30 | — | — | US | disclosed |
| US-20090314683-A1 | METHOD FOR PRODUCING HYDROCARBON FRACTIONS | JAPAN ENERGY CORPORATION (JP) | 2009-12-24 | — | — | US | disclosed |
| US-6589969-B1 | A peroxisome proliferator activated receptor regulator containing a compound of formula (I) Because of having an effect of regulating PPAR, a compound of formula (I) is useful as a hypoglycemic agent, a hypolipidemic agent, a preventive | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105572-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | HDAC1, HDAC7, HDAC5 | TSHR 2210/4885MAOB 2134/4885MAOA 2039/4885 |
| US-20100249197-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS | HDAC1, HDAC11, HDAC3 | TSHR 2764/4885MAOB 1742/4885MAOA 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.