Ethane

Ethane

SCHEMBL8632859

CC.CC[SiH2][Zr+2](C1C(C)=Cc2ccccc21)C1C(C)=Cc2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Ethane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL8633350 0.94 CYP3A4 (0.31)
Ethane SCHEMBL8636149 0.83
Propane SCHEMBL8632266 0.83 CYP11B1 (0.31) CYP11B1CYP11B2
Ethane SCHEMBL8633247 0.82
Hexane SCHEMBL8633801 0.82 CYP3A4 (0.31)
Hexane SCHEMBL8632251 0.78 CYP3A4 (0.31)
Hydrochloric Acid SCHEMBL29564384 0.77 CYP11B1 (0.33) CYP11B1CYP11B2
Ethane SCHEMBL8632942 0.76 PDCD1 (0.31)
Ethane SCHEMBL8634266 0.75
Ethane SCHEMBL8631684 0.75 KDM4E (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776851-A COORDINATION POLYMERIZATION CATALYST TARGOR GMBH (DE) 1998-07-07 US claimed
US-5776851-A COORDINATION POLYMERIZATION CATALYST TARGOR GMBH (DE) 1998-07-07 US disclosed