SCHEMBL8632928

SCHEMBL8632928

Oc1cc(Cl)c(Oc2ncc(C(F)(F)F)cc2Br)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.49
KMT2A Q03164 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 1/20 0.40
ALDH1A1 P00352 2/20 0.39
MRGPRX4 Q96LA9 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 1/20 0.38
PLAU P00749 1/20 0.38
SCN9A Q15858 1/20 0.37
GAA P10253 1/20 0.37
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8632798 0.87 RAB9A (0.63) RAB9AKMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL8634725 0.84 RAB9A (0.50) RAB9AKMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL7078847 0.84 RAB9A (0.43) RAB9AKMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL7078396 0.84 RAB9A (0.43) RAB9AKMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL8635553 0.80 RAB9A (0.40) RAB9AKMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL8638541 0.80 RAB9A (0.40) RAB9AKMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL8633200 0.78 CYP1A2 (0.45) RAB9AKMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL27399859 0.77 RAB9A (0.55) RAB9AKMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL9087915 0.77 RAB9A (0.37) RAB9AKMT2ACYP1A2CYP3A4CYP2C19
SCHEMBL9087917 0.77 RAB9A (0.37) RAB9AKMT2ACYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP claimed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP claimed
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed